Rochester fire officials say no civilians were hurt when fire broke out at a home on Weaver Street, near Remington Street.
A firefighter suffered a minor injury.
There were reports of people jumping from windows at the two story home, and the fire extended to the exterior of the house next door.
The cause is under investigation, but authorities say it was the second fire in the same home in two days.
City police say they detained one person involved in an alleged fight in the area last night. It's not clear if the fight was connected to the fire.